Orai and TRPC channel characterization in FcεRI‐mediated calcium signaling and mediator secretion in human mast cells

Inappropriate activation of mast cells via the Fcε RI receptor leads to the release of inflammatory mediators and symptoms of allergic disease. Calcium influx is a critical regulator of mast cell signaling and is required for exocytosis of preformed mediators and for synthesis of eicosanoids, cytoki...

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Detalles Bibliográficos
Autores principales: Wajdner, Hannah E., Farrington, Jasmine, Barnard, Claire, Peachell, Peter T., Schnackenberg, Christine G., Marino, Joseph P., Xu, Xiaoping, Affleck, Karen, Begg, Malcolm, Seward, Elizabeth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350174/
https://www.ncbi.nlm.nih.gov/pubmed/28292887
http://dx.doi.org/10.14814/phy2.13166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350174/
https://www.ncbi.nlm.nih.gov/pubmed/28292887
http://dx.doi.org/10.14814/phy2.13166

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