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CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury

We generated and studied CLIC1 null (C1KO) mice to investigate the physiological role of this protein. C1KO and matched wild‐type (WT) mice were studied in two models of acute toxic tissue injury. CLIC1 expression is upregulated following acute injury of WT kidney and pancreas and is absent in C1KOs...

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Detalles Bibliográficos
Autores principales: Ulmasov, Barbara, Bruno, Jonathan, Oshima, Kiyoko, Cheng, Yao‐Wen, Holly, Stephen P., Parise, Leslie V., Egan, Terrance M., Edwards, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350177/
https://www.ncbi.nlm.nih.gov/pubmed/28275112
http://dx.doi.org/10.14814/phy2.13169