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Differential responses of rabbit ventricular and atrial transient outward current (I(to)) to the I(to) modulator NS5806
Transient outward potassium current (I(to)) in the heart underlies phase 1 repolarization of cardiac action potentials and thereby affects excitation–contraction coupling. Small molecule activators of I(to) may therefore offer novel treatments for cardiac dysfunction, including heart failure and atr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350179/ https://www.ncbi.nlm.nih.gov/pubmed/28270595 http://dx.doi.org/10.14814/phy2.13172 |