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Differential responses of rabbit ventricular and atrial transient outward current (I(to)) to the I(to) modulator NS5806

Transient outward potassium current (I(to)) in the heart underlies phase 1 repolarization of cardiac action potentials and thereby affects excitation–contraction coupling. Small molecule activators of I(to) may therefore offer novel treatments for cardiac dysfunction, including heart failure and atr...

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Detalles Bibliográficos
Autores principales:	Cheng, Hongwei, Cannell, Mark B., Hancox, Jules C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350179/ https://www.ncbi.nlm.nih.gov/pubmed/28270595 http://dx.doi.org/10.14814/phy2.13172

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