The effects of dual PPARα/γ agonism compared with ACE inhibition in the BTBRob/ob mouse model of diabetes and diabetic nephropathy

The leptin‐deficient BTBRob/ob mouse develops progressive albuminuria and morphological lesions similar to human diabetic nephropathy (DN), although whether glomerular hyperfiltration, a recognized feature of early DN that may contribute to renal injury, also occurs in this model is not known. Lepti...

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Detalles Bibliográficos
Autores principales: Ericsson, Anette, Tonelius, Pernilla, Lal, Mark, Sabirsh, Alan, Böttcher, Gerhard, William‐Olsson, Lena, Strömstedt, Maria, Johansson, Camilla, Hyberg, Gina, Tapani, Sofia, Jönsson‐Rylander, Ann‐Cathrine, Unwin, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350186/
https://www.ncbi.nlm.nih.gov/pubmed/28292877
http://dx.doi.org/10.14814/phy2.13186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350186/
https://www.ncbi.nlm.nih.gov/pubmed/28292877
http://dx.doi.org/10.14814/phy2.13186

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