FGF treatment of host embryos injected with ES cells increases rates of chimaerism

In spite of the emergence of genome editing tools, ES cell mediated transgenesis remains the most controllable way of creating genetically modified animals. Although tetraploid (4N) complementation of 4N host embryos and ES cells, is the only method guaranteeing that offspring are entirely ES cell d...

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Detalles Bibliográficos
Autores principales: Dupont, Cathérine, Loos, Friedemann, Kong-A-San, John, Gribnau, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350236/
https://www.ncbi.nlm.nih.gov/pubmed/27873161
http://dx.doi.org/10.1007/s11248-016-9997-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350236/
https://www.ncbi.nlm.nih.gov/pubmed/27873161
http://dx.doi.org/10.1007/s11248-016-9997-6

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