Pentoxifylline Regulates Plasminogen Activator Inhibitor-1 Expression and Protein Kinase A Phosphorylation in Radiation-Induced Lung Fibrosis

Purpose. Radiation-induced lung fibrosis (RILF) is a serious late complication of radiotherapy. In vitro studies have demonstrated that pentoxifylline (PTX) has suppressing effects in extracellular matrix production in fibroblasts, while the antifibrotic action of PTX alone using clinical dose is ye...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Geol, Shim, Sehwan, Kim, Min-Jung, Myung, Jae Kyung, Jang, Won-Suk, Bae, Chang-Hwan, Lee, Sun-Joo, Kim, Kyeong Min, Jin, Young-Woo, Lee, Seung-Sook, Park, Sunhoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350299/
https://www.ncbi.nlm.nih.gov/pubmed/28337441
http://dx.doi.org/10.1155/2017/1279280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350299/
https://www.ncbi.nlm.nih.gov/pubmed/28337441
http://dx.doi.org/10.1155/2017/1279280

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