Molecular Mechanism for the Regulation of Microcystin Toxicity to Protein Phosphatase 1 by Glutathione Conjugation Pathway

Glutathione (GSH) conjugation was an important pathway to regulate the toxicity of microcystins (MCs) targeted to protein phosphatases. To explore the specific molecular mechanism for GSH detoxification, two typical MC-GSHs (derived from MCLR and MCRR) were synthesized, prepared, and purified accord...

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Detalles Bibliográficos
Autores principales: Zong, Wansong, Wang, Xiaoning, Du, Yonggang, Zhang, Shuhan, Zhang, Ying, Teng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350311/
https://www.ncbi.nlm.nih.gov/pubmed/28337461
http://dx.doi.org/10.1155/2017/9676504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350311/
https://www.ncbi.nlm.nih.gov/pubmed/28337461
http://dx.doi.org/10.1155/2017/9676504

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