Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short‐term facilitation at mossy fibre to CA3 pyramidal cell synapses

KEY POINTS: Neurodegenerative disorders can exhibit dysfunctional mitochondrial respiratory chain complex IV activity. Conditional deletion of cytochrome c oxidase, the terminal enzyme in the respiratory electron transport chain of mitochondria, from hippocampal dentate granule cells in mice does no...

Descripción completa

Detalles Bibliográficos
Autores principales: Booker, Sam A., Campbell, Graham R., Mysiak, Karolina S., Brophy, Peter J., Kind, Peter C., Mahad, Don J., Wyllie, David J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Neuroscience ‐ cellular/molecular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350446/
https://www.ncbi.nlm.nih.gov/pubmed/28083896
http://dx.doi.org/10.1113/JP273581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350446/
https://www.ncbi.nlm.nih.gov/pubmed/28083896
http://dx.doi.org/10.1113/JP273581

Ejemplares similares