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Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance

The potential for microbes to overcome antibiotics of different classes before they reach bacterial cells is largely unexplored. Here we show that a soluble bacterial lipocalin produced by Burkholderia cenocepacia upon exposure to sublethal antibiotic concentrations increases resistance to diverse a...

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Detalles Bibliográficos
Autores principales: El-Halfawy, Omar M., Klett, Javier, Ingram, Rebecca J., Loutet, Slade A., Murphy, Michael E. P., Martín-Santamaría, Sonsoles, Valvano, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350466/
https://www.ncbi.nlm.nih.gov/pubmed/28292982
http://dx.doi.org/10.1128/mBio.00225-17