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The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis
Metabolic energy reprogramming facilitates adaptations to a variety of stress conditions and cellular dysfunction, but how the energetic demands are monitored and met in response to physiological stimuli remains elusive. Our data support a model demonstrating that heat shock factor 1 (HSF1), a maste...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350514/ https://www.ncbi.nlm.nih.gov/pubmed/28183717 http://dx.doi.org/10.1083/jcb.201607091 |