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The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis

Metabolic energy reprogramming facilitates adaptations to a variety of stress conditions and cellular dysfunction, but how the energetic demands are monitored and met in response to physiological stimuli remains elusive. Our data support a model demonstrating that heat shock factor 1 (HSF1), a maste...

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Detalles Bibliográficos
Autores principales: Qiao, Aijun, Jin, Xiongjie, Pang, Junfeng, Moskophidis, Demetrius, Mivechi, Nahid F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350514/
https://www.ncbi.nlm.nih.gov/pubmed/28183717
http://dx.doi.org/10.1083/jcb.201607091