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Importin-11 keeps PTEN safe from harm
In this issue, Chen et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201604025) show that Importin-11 traffics the tumor suppressor PTEN into the nucleus and in so doing protects it from cytoplasmic proteins that cause PTEN degradation. This work helps explain the nuclear accumulation of PTEN...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350522/ https://www.ncbi.nlm.nih.gov/pubmed/28193699 http://dx.doi.org/10.1083/jcb.201612014 |