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A game of musical chairs: Pro- and anti-resection factors compete for TOPBP1 binding after DNA damage
DNA double strand breaks (DSBs) are generally repaired through nonhomologous end joining or homologous recombination. In this issue, Liu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607031) report that the conserved scaffold protein TOPBP1(Dpb11) provides binding sites for both pro- an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350523/ https://www.ncbi.nlm.nih.gov/pubmed/28235945 http://dx.doi.org/10.1083/jcb.201701038 |