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The peroxisomes strike BAK: Regulation of peroxisome integrity by the Bcl-2 family

Within the mitochondrial pathway of apoptosis, VDAC2 controls both the localization and proapoptotic activity of BAK. In this issue, Hosoi et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605002) find that loss of VDAC2 diverts BAK into peroxisome membranes, revealing the ability of BAK to...

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Detalles Bibliográficos
Autores principales: Chipuk, Jerry Edward, Luna-Vargas, Mark P.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350527/
https://www.ncbi.nlm.nih.gov/pubmed/28193702
http://dx.doi.org/10.1083/jcb.201701187