ZRF1 is a novel S6 kinase substrate that drives the senescence programme

The inactivation of S6 kinases mimics several aspects of caloric restriction, including small body size, increased insulin sensitivity and longevity. However, the impact of S6 kinase activity on cellular senescence remains to be established. Here, we show that the constitutive activation of mammalia...

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Detalles Bibliográficos
Autores principales: Barilari, Manuela, Bonfils, Gregory, Treins, Caroline, Koka, Vonda, De Villeneuve, Delphine, Fabrega, Sylvie, Pende, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350561/
https://www.ncbi.nlm.nih.gov/pubmed/28242756
http://dx.doi.org/10.15252/embj.201694966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350561/
https://www.ncbi.nlm.nih.gov/pubmed/28242756
http://dx.doi.org/10.15252/embj.201694966

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