Insights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase model

In higher eukaryotes, cell proliferation is regulated by class I phosphatidylinositol 3-kinase (PI3K), which transduces stimuli received from neighboring receptors by local generation of PtdIns(3,4,5)P(3) in cellular membranes. PI3K is a heterodimeric protein consisting of a regulatory and a catalyt...

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Detalles Bibliográficos
Autores principales: Oliver, María D., Fernández-Acero, Teresa, Luna, Sandra, Rodríguez-Escudero, Isabel, Molina, María, Pulido, Rafael, Cid, Víctor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350601/
https://www.ncbi.nlm.nih.gov/pubmed/28143957
http://dx.doi.org/10.1042/BSR20160258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350601/
https://www.ncbi.nlm.nih.gov/pubmed/28143957
http://dx.doi.org/10.1042/BSR20160258

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