Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β

The double-stranded RNA mimetic poly(I:C) and lipopolysaccharide (LPS) activate Toll-like receptors 3 (TLR3) and TLR4, respectively, triggering the activation of TANK (TRAF family member-associated NF-κB activator)-binding kinase 1 (TBK1) complexes, the phosphorylation of interferon regulatory facto...

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Detalles Bibliográficos
Autores principales: Bakshi, Siddharth, Taylor, Jordan, Strickson, Sam, McCartney, Thomas, Cohen, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350611/
https://www.ncbi.nlm.nih.gov/pubmed/28159912
http://dx.doi.org/10.1042/BCJ20160992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350611/
https://www.ncbi.nlm.nih.gov/pubmed/28159912
http://dx.doi.org/10.1042/BCJ20160992

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