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Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β

The double-stranded RNA mimetic poly(I:C) and lipopolysaccharide (LPS) activate Toll-like receptors 3 (TLR3) and TLR4, respectively, triggering the activation of TANK (TRAF family member-associated NF-κB activator)-binding kinase 1 (TBK1) complexes, the phosphorylation of interferon regulatory facto...

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Detalles Bibliográficos
Autores principales:	Bakshi, Siddharth, Taylor, Jordan, Strickson, Sam, McCartney, Thomas, Cohen, Philip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350611/ https://www.ncbi.nlm.nih.gov/pubmed/28159912 http://dx.doi.org/10.1042/BCJ20160992

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