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Quantifying Beta‐Galactosylceramide Kinetics in Cerebrospinal Fluid of Healthy Subjects Using Deuterium Labeling

Therapeutics promoting myelin synthesis may enhance recovery in demyelinating diseases, such as multiple sclerosis. However, no suitable method exists to quantify myelination. The turnover of galactosylceramide (myelin component) is indicative of myelination in mice, but its turnover has not been de...

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Detalles Bibliográficos
Autores principales: Kanhai, KMS, Goulooze, SC, Stevens, J, Hay, JL, Dent, G, Verma, A, Hankemeier, T, de Boer, T, Meijering, H, Chavez, JC, Cohen, AF, Groeneveld, GJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351000/
https://www.ncbi.nlm.nih.gov/pubmed/27743499
http://dx.doi.org/10.1111/cts.12424