Translational Pharmacokinetic/Pharmacodynamic Analysis of MYO‐029 Antibody for Muscular Dystrophy

Suppression of the myostatin (GDF‐8) pathway has emerged as an important therapeutic paradigm for muscle‐wasting disorders. In this study, we conducted a translational pharmacokinetic/pharmacodynamic (PK/PD) analysis of MYO‐029, an anti‐myostatin monoclonal antibody, using PK data in mice, rats, mon...

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Detalles Bibliográficos
Autores principales: Singh, P, Rong, H, Gordi, T, Bosley, J, Bhattacharya, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351001/
https://www.ncbi.nlm.nih.gov/pubmed/27700008
http://dx.doi.org/10.1111/cts.12420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351001/
https://www.ncbi.nlm.nih.gov/pubmed/27700008
http://dx.doi.org/10.1111/cts.12420

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