PTTG1 Levels Are Predictive of Saracatinib Sensitivity in Ovarian Cancer Cell Lines

Src kinase is recognized as a key target for molecular cancer therapy. However, methods to efficiently select patients responsive to Src inhibitors are lacking. We explored the sensitivity of ovarian cancer cell lines to the Src kinase inhibitor saracatinib to identify predictive markers of drug sen...

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Detalles Bibliográficos
Autores principales: Nakachi, I, Helfrich, BA, Spillman, MA, Mickler, EA, Olson, CJ, Rice, JL, Coldren, CD, Heasley, LE, Geraci, MW, Stearman, RS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351005/
https://www.ncbi.nlm.nih.gov/pubmed/27766744
http://dx.doi.org/10.1111/cts.12413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351005/
https://www.ncbi.nlm.nih.gov/pubmed/27766744
http://dx.doi.org/10.1111/cts.12413

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