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Ursolic acid sensitizes radioresistant NSCLC cells expressing HIF-1α through reducing endogenous GSH and inhibiting HIF-1α

In previous studies, the present authors demonstrated that effective sensitization of ionizing radiation-induced death of tumor cells, including non-small cell lung cancer (NSCLC) cells, could be produced by oleanolic acid (OA), a pentacyclic triterpenoid present in plants. In the present study, it...

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Detalles Bibliográficos
Autores principales: Song, Bing, Zhang, Qian, Yu, Maohu, Qi, Xinrong, Wang, Gang, Xiao, Linlin, Yi, Qiyi, Jin, Wensen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351155/
https://www.ncbi.nlm.nih.gov/pubmed/28356955
http://dx.doi.org/10.3892/ol.2016.5468