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Comprehensive discovery of subsample gene expression components by information explanation: therapeutic implications in cancer
BACKGROUND: De novo inference of clinically relevant gene function relationships from tumor RNA-seq remains a challenging task. Current methods typically either partition patient samples into a few subtypes or rely upon analysis of pairwise gene correlations that will miss some groups in noisy data....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351169/ https://www.ncbi.nlm.nih.gov/pubmed/28292312 http://dx.doi.org/10.1186/s12920-017-0245-6 |