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Comprehensive discovery of subsample gene expression components by information explanation: therapeutic implications in cancer

BACKGROUND: De novo inference of clinically relevant gene function relationships from tumor RNA-seq remains a challenging task. Current methods typically either partition patient samples into a few subtypes or rely upon analysis of pairwise gene correlations that will miss some groups in noisy data....

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Detalles Bibliográficos
Autores principales: Pepke, Shirley, Ver Steeg, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351169/
https://www.ncbi.nlm.nih.gov/pubmed/28292312
http://dx.doi.org/10.1186/s12920-017-0245-6