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A malignant inflammatory myofibroblastic tumor of the hypopharynx harboring the 3a/b variants of the EML4-ALK fusion gene

Inflammatory myofibroblastic tumors (IMT) in the head and neck region are rare neoplasms that generally mimic benign/low-grade neoplasms. Overexpression of anaplastic lymphoma kinase (ALK) has been reported in 50% of IMT cases, secondary to ALK activation by structural rearrangements in the ALK gene...

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Detalles Bibliográficos
Autores principales: Muscarella, Lucia Anna, Rossi, Giulio, Trombetta, Domenico, La Torre, Annamaria, Di Candia, Leonarda, Mengoli, Maria Cecilia, Sparaneo, Angelo, Fazio, Vito Michele, Graziano, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351184/
https://www.ncbi.nlm.nih.gov/pubmed/28356934
http://dx.doi.org/10.3892/ol.2016.5504