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Exaggerated CpH methylation in the autism-affected brain

BACKGROUND: The etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the development of autism, we explored the role of CpG and CpH (H = A, C, or T) methylatio...

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Detalles Bibliográficos
Autores principales: Ellis, Shannon E., Gupta, Simone, Moes, Anna, West, Andrew B., Arking, Dan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351204/
https://www.ncbi.nlm.nih.gov/pubmed/28316770
http://dx.doi.org/10.1186/s13229-017-0119-y