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Characterizing Class‐Specific Exposure‐Viral Load Suppression Response of HIV Antiretrovirals Using A Model‐Based Meta‐Analysis

We applied model‐based meta‐analysis of viral suppression as a function of drug exposure and in vitro potency for short‐term monotherapy in human immunodeficiency virus type 1 (HIV‐1)‐infected treatment‐naïve patients to set pharmacokinetic targets for development of nonnucleoside reverse transcript...

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Detalles Bibliográficos
Autores principales: Xu, Y, Li, YF, Zhang, D, Dockendorf, M, Tetteh, E, Rizk, ML, Grobler, JA, Lai, M‐T, Gobburu, J, Ankrom, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351339/
https://www.ncbi.nlm.nih.gov/pubmed/27171172
http://dx.doi.org/10.1111/cts.12395