Prediction of in vivo and in vitro infection model results using a semimechanistic model of avibactam and aztreonam combination against multidrug resistant organisms

The combination of aztreonam‐avibactam is active against multidrug‐resistant Enterobacteriaceae that express metallo‐β‐lactamases. A complex synergistic interaction exists between aztreonam and avibactam bactericidal activities that have not been quantitatively explored. A two‐state semimechanistic...

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Detalles Bibliográficos
Autores principales: Sy, SKB, Zhuang, L, Xia, H, Beaudoin, M‐E, Schuck, VJ, Derendorf, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351411/
https://www.ncbi.nlm.nih.gov/pubmed/28145085
http://dx.doi.org/10.1002/psp4.12159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351411/
https://www.ncbi.nlm.nih.gov/pubmed/28145085
http://dx.doi.org/10.1002/psp4.12159

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