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Mathematical modeling of the effects of CK2.3 on mineralization in osteoporotic bone

Osteoporosis is caused by decreased bone mineral density (BMD) and new treatments for this disease are desperately needed. Bone morphogenetic protein 2 (BMP2) is crucial for bone formation. The mimetic peptide CK2.3 acts downstream of BMP2 and increases BMD when injected systemically into the tail v...

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Detalles Bibliográficos
Autores principales: Lisberg, A, Ellis, R, Nicholson, K, Moku, P, Swarup, A, Dhurjati, P, Nohe, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351412/
https://www.ncbi.nlm.nih.gov/pubmed/28181418
http://dx.doi.org/10.1002/psp4.12154