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IODNE: An integrated optimization method for identifying the deregulated subnetwork for precision medicine in cancer
Subnetwork analysis can explore complex patterns of entire molecular pathways for the purpose of drug target identification. In this article, the gene expression profiles of a cohort of patients with breast cancer are integrated with protein‐protein interaction (PPI) networks using, simultaneously,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351413/ https://www.ncbi.nlm.nih.gov/pubmed/28266149 http://dx.doi.org/10.1002/psp4.12167 |