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IODNE: An integrated optimization method for identifying the deregulated subnetwork for precision medicine in cancer

Subnetwork analysis can explore complex patterns of entire molecular pathways for the purpose of drug target identification. In this article, the gene expression profiles of a cohort of patients with breast cancer are integrated with protein‐protein interaction (PPI) networks using, simultaneously,...

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Detalles Bibliográficos
Autores principales: Mounika Inavolu, S, Renbarger, J, Radovich, M, Vasudevaraja, V, Kinnebrew, GH, Zhang, S, Cheng, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351413/
https://www.ncbi.nlm.nih.gov/pubmed/28266149
http://dx.doi.org/10.1002/psp4.12167

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