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Reduced perfusion in systemic sclerosis digital ulcers (both fingertip and extensor) can be increased by topical application of glyceryl trinitrate()

OBJECTIVES: In patients with systemic sclerosis (SSc), fingertip digital ulcers (DUs) are believed to be ischaemic, and extensor surface DUs a result of mechanical factors/microtrauma. Our aim was to assess blood flow response to topical glyceryl trinitrate (GTN) compared to placebo in SSc DUs, look...

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Detalles Bibliográficos
Autores principales: Hughes, M., Moore, T., Manning, J., Wilkinson, J., Dinsdale, G., Roberts, C., Murray, A., Herrick, A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351498/
https://www.ncbi.nlm.nih.gov/pubmed/28027937
http://dx.doi.org/10.1016/j.mvr.2016.12.008