Accurate self-correction of errors in long reads using de Bruijn graphs

MOTIVATION: New long read sequencing technologies, like PacBio SMRT and Oxford NanoPore, can produce sequencing reads up to 50 000 bp long but with an error rate of at least 15%. Reducing the error rate is necessary for subsequent utilization of the reads in, e.g. de novo genome assembly. The error...

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Detalles Bibliográficos
Autores principales: Salmela, Leena, Walve, Riku, Rivals, Eric, Ukkonen, Esko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Recomb-Seq/Recomb-Cbb 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351550/
https://www.ncbi.nlm.nih.gov/pubmed/27273673
http://dx.doi.org/10.1093/bioinformatics/btw321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351550/
https://www.ncbi.nlm.nih.gov/pubmed/27273673
http://dx.doi.org/10.1093/bioinformatics/btw321

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