Total DNA input is a crucial determinant of the sensitivity of plasma cell-free DNA EGFR mutation detection using droplet digital PCR

We evaluated the use of droplet digital PCR (ddPCR) to detect plasma cell-free DNA (cfDNA) epidermal growth factor receptor (EGFR) mutations in advanced non-small cell lung cancer (NSCLC) patients. Compared with tumor-tissue-based detection, the sensitivity of ddPCR for detecting plasma cfDNA tyrosi...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Xu, Yan, Zhong, Wei, Zhao, Jing, Chen, Minjiang, Zhang, Li, Li, Longyun, Wang, Mengzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351596/
https://www.ncbi.nlm.nih.gov/pubmed/28052016
http://dx.doi.org/10.18632/oncotarget.14390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351596/
https://www.ncbi.nlm.nih.gov/pubmed/28052016
http://dx.doi.org/10.18632/oncotarget.14390

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