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A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts

Next-generation sequencing (NGS) can identify and validate new biomarkers of cancer onset, progression and therapy resistance. Substantial archives of formalin-fixed, paraffin-embedded (FFPE) cancer samples from patients represent a rich resource for linking molecular signatures to clinical data. Ho...

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Detalles Bibliográficos
Autores principales: Hoover, Malachia, Adamian, Yvess, Brown, Mark, Maawy, Ali, Chang, Alexander, Lee, Jacqueline, Gharibi, Armen, Katz, Matthew H, Fleming, Jason, Hoffman, Robert M, Bouvet, Michael, Doebler, Robert, Kelber, Jonathan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351598/
https://www.ncbi.nlm.nih.gov/pubmed/27602776
http://dx.doi.org/10.18632/oncotarget.11809