A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer

The DNA mismatch repair (MMR) system corrects DNA replication mismatches thereby contributing to the maintenance of genomic stability. MMR deficiency has been observed in prostate cancer but its impact on the genomic landscape of these tumours is not known. In order to identify MMR associated mutati...

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Detalles Bibliográficos
Autores principales: Alves, Inês Teles, Cano, David, Böttcher, René, van der Korput, Hetty, Dinjens, Winand, Jenster, Guido, Trapman, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351611/
https://www.ncbi.nlm.nih.gov/pubmed/27907910
http://dx.doi.org/10.18632/oncotarget.13464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351611/
https://www.ncbi.nlm.nih.gov/pubmed/27907910
http://dx.doi.org/10.18632/oncotarget.13464

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