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A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer
The DNA mismatch repair (MMR) system corrects DNA replication mismatches thereby contributing to the maintenance of genomic stability. MMR deficiency has been observed in prostate cancer but its impact on the genomic landscape of these tumours is not known. In order to identify MMR associated mutati...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351611/ https://www.ncbi.nlm.nih.gov/pubmed/27907910 http://dx.doi.org/10.18632/oncotarget.13464 |