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MBD3 inhibits formation of liver cancer stem cells

Liver cancer cells can be reprogrammed into induced cancer stem cells (iCSCs) by exogenous expression of the reprogramming transcription factors Oct4, Sox2, Klf4 and c-Myc (OSKM). The nucleosome remodeling and deacetylase (NuRD) complex is essential for reprogramming somatic cells. In this study, we...

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Detalles Bibliográficos
Autores principales: Li, Ruizhi, He, Qihua, Han, Shuo, Zhang, Mingzhi, Liu, Jinwen, Su, Ming, Wei, Shiruo, Wang, Xuan, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351613/
https://www.ncbi.nlm.nih.gov/pubmed/27894081
http://dx.doi.org/10.18632/oncotarget.13496