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Dysregulated miR34a/diacylglycerol kinase ζ interaction enhances T-cell activation in acquired aplastic anemia

Acquired aplastic anemia is an idiopathic paradigm of human bone marrow failure syndrome, which involves active destruction of hematopoietic stem cells and progenitors by cytotoxic T cells in the bone marrow. Aberrant expression of microRNAs in T cells has been shown to lead to development of certai...

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Detalles Bibliográficos
Autores principales: Sun, Yuan-xin, Li, Hui, Feng, Qi, Li, Xin, Yu, Ying-yi, Zhou, Li-wei, Gao, Yan, Li, Guo-sheng, Ren, Juan, Ma, Chun-hong, Gao, Cheng-jiang, Peng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351619/
https://www.ncbi.nlm.nih.gov/pubmed/28008152
http://dx.doi.org/10.18632/oncotarget.14046