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Radiolabeled novel mAb 4G1 for immunoSPECT imaging of EGFRvIII expression in preclinical glioblastoma xenografts

Epidermal growth factor receptor mutant III (EGFRvIII) is exclusively expressed in tumors, such as glioblastoma, breast cancer and hepatocellular carcinoma, but never in normal organs. Increasing evidence suggests that EGFRvIII has clinical significance in glioblastoma prognosis due to its enhanced...

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Detalles Bibliográficos
Autores principales: Liu, Xujie, Dong, Chengyan, Shi, Jiyun, Ma, Teng, Jin, Zhongxia, Jia, Bing, Liu, Zhaofei, Shen, Li, Wang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351638/
https://www.ncbi.nlm.nih.gov/pubmed/28031526
http://dx.doi.org/10.18632/oncotarget.14088