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Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism

The importance of iron in the growth and progression of tumors has been widely documented. In this report, we show that tumor-initiating cells (TICs), represented by spheres derived from the MCF7 cell line, exhibit higher intracellular labile iron pool, mitochondrial iron accumulation and are more s...

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Detalles Bibliográficos
Autores principales: Rychtarcikova, Zuzana, Lettlova, Sandra, Tomkova, Veronika, Korenkova, Vlasta, Langerova, Lucie, Simonova, Ekaterina, Zjablovskaja, Polina, Alberich-Jorda, Meritxell, Neuzil, Jiri, Truksa, Jaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351639/
https://www.ncbi.nlm.nih.gov/pubmed/28031527
http://dx.doi.org/10.18632/oncotarget.14093