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Activation of ATR-Chk1 pathway facilitates EBV-mediated transformation of primary tonsillar B-cells

Primary infection of the immunocompromised host with the oncovirus Epstein-Barr virus (EBV) that targets mainly B-cells is associated with an increased risk for EBV-associated tumors. The early events subsequent to primary infection with potential for B-cell transformation are poorly studied. Here,...

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Detalles Bibliográficos
Autores principales: Mordasini, Vanessa, Ueda, Seigo, Aslandogmus, Roberta, Berger, Christoph, Gysin, Claudine, Hühn, Daniela, Sartori, Alessandro A, Bernasconi, Michele, Nadal, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351645/
https://www.ncbi.nlm.nih.gov/pubmed/28031537
http://dx.doi.org/10.18632/oncotarget.14120