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Recurrent genetic defects on chromosome 5q in myeloid neoplasms

BACKGROUND: Deletion of chromosome 5q (del(5q)) is the most common karyotypic abnormality in myeloid neoplasms. MATERIALS AND METHODS: To define the pathogenic molecular features associated with del(5q), next–generation sequencing was applied to 133 patients with myeloid neoplasms (MDS; N = 69, MDS/...

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Detalles Bibliográficos
Autores principales: Hosono, Naoko, Makishima, Hideki, Mahfouz, Reda, Przychodzen, Bartlomiej, Yoshida, Kenichi, Jerez, Andres, LaFramboise, Thomas, Polprasert, Chantana, Clemente, Michael J, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Sanada, Masashi, Cui, Edward, Verma, Amit K, McDevitt, Michael A, List, Alan F, Saunthararajah, Yogen, Sekeres, Mikkael A, Boultwood, Jacqueline, Ogawa, Seishi, Maciejewski, Jaroslaw P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351647/
https://www.ncbi.nlm.nih.gov/pubmed/28031539
http://dx.doi.org/10.18632/oncotarget.14130