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Targeted delivery of nano-PTX to the brain tumor-associated macrophages

Nanoparticles containing mixed lipid monolayer shell, biodegradable polymer core and rabies virus glycoprotein (RVG) peptide as brain targeting ligand, were developed for brain targeted delivery of paclitaxel (PTX) to treat malignant glioma. RVG conjugated PTX loaded NPs (RVG-PTX-NPs) had the desira...

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Detalles Bibliográficos
Autores principales: Zou, Lei, Tao, Youhua, Payne, Gregory, Do, Linh, Thomas, Tima, Rodriguez, Juan, Dou, Huanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351653/
https://www.ncbi.nlm.nih.gov/pubmed/28036254
http://dx.doi.org/10.18632/oncotarget.14169