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Whole-exome sequencing identified mutational profiles of high-grade colon adenomas

Although gene-to-gene analyses identified genetic alterations such as APC, KRAS and TP53 mutations in colon adenomas, it is largely unknown whether there are any others in them. Mutational profiling of high-grade colon adenoma (HGCA) that just precedes colon carcinoma might identify not only novel a...

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Detalles Bibliográficos
Autores principales: Lee, Sung Hak, Hyun, Seung Jung, Kim, Tae-Min, Rhee, Je-Keun, Park, Hyeon-Chun, Sung, Min Kim, Kim, Sung Soo, Hyeok, Chang An, Lee Hyung, Sug, Chung, Yeun-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351654/
https://www.ncbi.nlm.nih.gov/pubmed/28179590
http://dx.doi.org/10.18632/oncotarget.14172