The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma

The long non-coding RNA GAS5 has been shown to modulate cancer proliferation in numerous human cancer systems and has been correlated with successful patient outcome. Our examination of GAS5 in neuroblastoma has revealed robust expression in both MYCN-amplified and non-amplified cell lines. Knockdow...

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Detalles Bibliográficos
Autores principales: Mazar, Joseph, Rosado, Amy, Shelley, John, Marchica, John, Westmoreland, Tamarah J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351655/
https://www.ncbi.nlm.nih.gov/pubmed/28035057
http://dx.doi.org/10.18632/oncotarget.14244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351655/
https://www.ncbi.nlm.nih.gov/pubmed/28035057
http://dx.doi.org/10.18632/oncotarget.14244

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