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The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma
The long non-coding RNA GAS5 has been shown to modulate cancer proliferation in numerous human cancer systems and has been correlated with successful patient outcome. Our examination of GAS5 in neuroblastoma has revealed robust expression in both MYCN-amplified and non-amplified cell lines. Knockdow...
Autores principales: | Mazar, Joseph, Rosado, Amy, Shelley, John, Marchica, John, Westmoreland, Tamarah J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351655/ https://www.ncbi.nlm.nih.gov/pubmed/28035057 http://dx.doi.org/10.18632/oncotarget.14244 |
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