Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells

Autophagy is the process of lysosome-mediated degradation and recycling that functions as an adaptive survival mechanism during anti-cancer therapy. Aberrant activation of the phosphoinositide-3-kinase (PI3K) pathway frequently occurs in solid tumors, including cervical cancer. However, single-agent...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hyun-Jung, Lee Yoon, Soo, Young, Chan Kim, Hwan, Yun Kim, Ju, Woong, Cheol, Seung Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351656/
https://www.ncbi.nlm.nih.gov/pubmed/28036259
http://dx.doi.org/10.18632/oncotarget.14245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351656/
https://www.ncbi.nlm.nih.gov/pubmed/28036259
http://dx.doi.org/10.18632/oncotarget.14245

Ejemplares similares