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Positive feedback loop of IL-1β/Akt/RARα/Akt signaling mediates oncogenic property of RARα in gastric carcinoma

Abnormal expression and function of retinoic acid receptor α (RARα) have been reported to be associated with various cancers including acute promyelocytic leukemia and hepatocellular carcinoma. However, the role and the mechanism of RARα in gastric carcinoma (GC) were unknown. Here, the expression o...

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Detalles Bibliográficos
Autores principales: Ren, Hong-Yue, Liu, Fan, Huang, Gui-Li, Liu, Yu, Shen, Jin-Xing, Zhou, Pan, Liu, Wen-Ming, Shen, Dong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351665/
https://www.ncbi.nlm.nih.gov/pubmed/28035062
http://dx.doi.org/10.18632/oncotarget.14267