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EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

EglN2 contributes to ERα-positive breast tumorigenesis by acting as an estrogen-inducible gene. However, the detailed molecular mechanism(s) underlying the post-transcriptional regulation of EglN2 and its potential role in Triple Negative Breast Cancer (TNBC) remains largely unclear. By using C3Tag...

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Detalles Bibliográficos
Autores principales: Takada, Mamoru, Zhuang, Ming, Inuzuka, Hiroyuki, Zhang, Jing, Zurlo, Giada, Zhang, Jinfang, Zhang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351669/
https://www.ncbi.nlm.nih.gov/pubmed/28036276
http://dx.doi.org/10.18632/oncotarget.14290