N-glycosylation converts non-glycoproteins into mannose receptor ligands and reveals antigen-specific T cell responses in vivo

N-glycosylation is generally accepted to enhance the immunogenicity of antigens because of two main reasons. First, the attachment of glycans enables recognition by endocytic receptors like the mannose receptor (MR) and hence increased uptake by dendritic cells (DCs). Second, foreign glycans are pos...

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Detalles Bibliográficos
Autores principales: Kreer, Christoph, Kuepper, Janina M, Zehner, Matthias, Quast, Thomas, Kolanus, Waldemar, Schumak, Beatrix, Burgdorf, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351675/
https://www.ncbi.nlm.nih.gov/pubmed/28036287
http://dx.doi.org/10.18632/oncotarget.14314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351675/
https://www.ncbi.nlm.nih.gov/pubmed/28036287
http://dx.doi.org/10.18632/oncotarget.14314

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